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采用~(201)铊显象的潘生丁试验迄今已广泛用于临床,但潘生丁是否引起灌注不均或减少阻塞血管的血流量,诱发确凿的心肌缺血或影响左室功能尚未清楚。作者通过大量预测研究表明:经由核素心室显象所示的左室扩张与功能不全系潘生丁诱发心肌缺血的有力佐证。病人与方法:145例分成可疑冠脉疾病组[Ⅰ组:32例。其中男23,女9,平均年龄59岁(40~76岁)]与冠脉疾病组[Ⅰ组:113例,其中男101,女12,平均年龄59岁(41~81岁)]。Ⅰ组仅发生与劳累不相关的非特异性胸痛,查体、ECG、UCG、~(201)铊显象及冠脉造影等基本正常。Ⅱ组具有典型劳力型心绞痛发作,经休息和服硝酸盐后能缓解;71例有心肌梗塞史;冠脉造影示冠脉狭窄>60%的单支病变者19
The dipyridamole test using ~ (201) thallium imaging has so far been widely used clinically, but it remains unclear whether dipyridamole causes uneven perfusion or reduces occlusion of blood vessels, induces conclusive myocardial ischemia or affects left ventricular function. The authors through a large number of predictive studies have shown that: via radionuclide ventricular imaging shown in the left ventricular dilatation and inadequate systolic blood pressure induced by dipyridamole strong evidence. Patients and Methods: 145 cases were divided into suspicious coronary artery disease group [group Ⅰ: 32 cases. Male 23, female 9, mean age 59 years (40-76 years)] and coronary disease group [group I: 113 cases, male 101, female 12, mean age 59 years (41-81 years)]. In group Ⅰ, only nonspecific chest pain unrelated to exertion, physical examination, ECG, UCG, ~ (201) thallium imaging and coronary angiography were found. Group Ⅱ had typical exertional angina pectoris, which could be relieved by resting and taking nitrates; 71 patients had a history of myocardial infarction; coronary angiography showed coronary stenosis> 60% of single-vessel lesions 19