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目的:比较醋柳黄酮与丹参治疗高脂、高粘血症病人的疗效。方法:治疗组35例(全部男性,年龄52±s8a)用醋柳黄酮20mg,po,tid。对照组34例(全部男性,年龄51±9a)用丹参10mL,po,bid。疗程均为6wk。结果:治疗组血胆固醇(TC)、三酰甘油(TG)、载脂蛋白B100(ApoB100)、血浆凝血因子I、血液粘度、血小板聚集率和血栓指数均较治疗前有显著(P<0.05)或极显著(P<0.01)下降。对照组在10·s-1血液粘度较治疗前有极显著下降(P<0.01),在100·s-1血液粘度和血栓指数较治疗前有显著下降(P<0.05)。结论:醋柳黄酮治疗后,大部分指标(除10·s-1血液粘度指标外)下降,优于丹参。
Objective: To compare the curative effect of tipplewort and salvia miltiorrhiza in treating patients with hyperlipidemia and hyperviscosity. Methods: The treatment group, 35 cases (all men, age 52 ± s8a) with tiil flavonoids 20mg, po, tid. Control group of 34 patients (all men, age 51 ± 9a) with Salvia 10mL, po, bid. Treatment are 6wk. Results: The levels of TC, TG, ApoB100, plasma coagulation factor I, blood viscosity, platelet aggregation rate and thrombosis index in treatment group were significantly higher than those before treatment (P <0. 05) or very significant (P <0.01) decreased. The blood viscosity of 10 · s-1 in control group was significantly lower than that before treatment (P <0.01), and the viscosity and thrombosis index of 100 · s-1 decreased significantly (P <0.05). CONCLUSION: Most of the indexes (except the 10 · s-1 blood viscosity index) decreased after the treatment with tihling flavonoids, which was better than that of Salvia miltiorrhiza.