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对28家医院1986~1996年间的430例胆囊癌行回顾性分析。结果:(1)胆囊癌老年女性多见。(2)胆囊癌占同期胆道疾病的1.6%,并存胆结石发生率50%。(3)临床表现为上腹痛、恶心、黄疸等。(4)以胆囊腺癌为主,填满型胆囊癌最多(58%)。(5)胆管转移(68.5%)和肝脏转移(30%)是主要转移方式。(6)B超和CT阳性诊断率分别为77%和66%,近5年其对早、中期胆囊癌的术前诊断率显著提高(P<0.05)。(7)Ⅰ、Ⅱ期胆囊癌手术切除率100%,Ⅲ、Ⅳ期75%,Ⅴ期显著降低(P<0.05)。(8)Ⅰ、Ⅱ期胆囊癌手术后3年生存率显著高于中晚期(P<0.05)。
A retrospective analysis of 430 gallbladder cancers in 28 hospitals between 1986 and 1996 was performed. Results: (1) Elderly women with gallbladder cancer were more common. (2) Gallbladder cancer accounted for 1.6% of biliary tract disease at the same time, and the incidence of gallstones was 50%. (3) The clinical manifestations were epigastric pain, nausea, and jaundice. (4) Gallbladder adenocarcinoma was the main type, and gallbladder carcinoma was most filled (58%). (5) Bile duct metastasis (68.5%) and liver metastasis (30%) are the major metastatic methods. (6) The positive rates of B-scan and CT were 77% and 66% respectively, and the preoperative diagnosis rate of gallbladder cancer in the early and mid-term was significantly higher in the past 5 years (P<0.05). (7) The resection rate of stage I and II gallbladder carcinoma was 100%, 75% in stage III and IV, and V stage was significantly decreased (P<0.05). (8) The 3-year survival rate of stage I and II gallbladder cancer was significantly higher than that of the middle and late stage (P<0.05).