对２８家医院１９８６～１９９６年间的４３０例胆囊癌行回顾性分析。结果：（１）胆囊癌老年女性多见。（２）胆囊癌占同期胆道疾病的１．６％，并存胆结石发生率５０％。（３）临床表现为上腹痛、恶心、黄疸等。（４）以胆囊腺癌为主，填满型胆囊癌最多（５８％）。（５）胆管转移（６８．５％）和肝脏转移（３０％）是主要转移方式。（６）Ｂ超和ＣＴ阳性诊断率分别为７７％和６６％，近５年其对早、中期胆囊癌的术前诊断率显著提高（Ｐ＜０．０５）。（７）Ⅰ、Ⅱ期胆囊癌手术切除率１００％，Ⅲ、Ⅳ期７５％，Ⅴ期显著降低（Ｐ＜０．０５）。（８）Ⅰ、Ⅱ期胆囊癌手术后３年生存率显著高于中晚期（Ｐ＜０．０５）。 A retrospective analysis of 430 gallbladder cancers in 28 hospitals between 1986 and 1996 was performed. Results: (1) Elderly women with gallbladder cancer were more common. (2) Gallbladder cancer accounted for 1.6% of biliary tract disease at the same time, and the incidence of gallstones was 50%. (3) The clinical manifestations were epigastric pain, nausea, and jaundice. (4) Gallbladder adenocarcinoma was the main type, and gallbladder carcinoma was most filled (58%). (5) Bile duct metastasis (68.5%) and liver metastasis (30%) are the major metastatic methods. (6) The positive rates of B-scan and CT were 77% and 66% respectively, and the preoperative diagnosis rate of gallbladder cancer in the early and mid-term was significantly higher in the past 5 years (P<0.05). (7) The resection rate of stage I and II gallbladder carcinoma was 100%, 75% in stage III and IV, and V stage was significantly decreased (P<0.05). (8) The 3-year survival rate of stage I and II gallbladder cancer was significantly higher than that of the middle and late stage (P<0.05).