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背景 最近,一份关于注射吸毒者调查数据表明,HCV血清阳性黑人中持续HCV病毒血症血清阳性的比率(B:91％)较非黑色人种的(W:64％)高5倍(RIBA确证实验),提示可能存在病毒清除的遗传决定因子(JAMM 2000;284;450—6)。其它的研究表明年龄与病毒的清除之间存在相关关系。在过去的2年中,用NAT法筛选供血者HCV RNA的常规资料提供了大量资料用以分析血清阳性人群当中持续病毒血症的联系。方法 调查来
Background Recently, a survey of injecting drug users showed that the prevalence of persistent HCV viremia seropositivity (B: 91%) in HCV seropositive blacks is five times higher than that of non-black human (W: 64%) (RIBA Confirmatory experiments), suggesting that there may be a genetic determinant of virus clearance (JAMM 2000; 284; 450-6). Other studies show a correlation between age and viral clearance. In the past two years, routine screening of donor blood for HCV RNA using the NAT method has provided a wealth of data for the analysis of persistent viremia in seropositive populations. Methodological survey came