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目的探讨杀虫脒急性中毒是否全数或多数出现高铁血红蛋白血症。方法采用氰化高铁血红蛋白光电比色法测定杀虫脒急性中毒大鼠、家兔、家鸽及亚硝酸钠急性中毒家鸽血样中高铁血红蛋白的含量。结果上述杀虫脒急性中毒动物的血样中高铁血红蛋白的含量均属正常范围,而亚硝酸钠急性中毒家鸽血样中高铁血红蛋白的含量明显增加,二巯基丙磺酸钠不能还原由亚硝酸钠所致的高铁血红蛋白。结论杀虫脒急性中毒并非全数或多数出现高铁血红蛋白血症,高铁血红蛋白血症也并非是杀虫脒急性中毒死亡的主要原因。
Objective To investigate whether all or most of metchidine amidine poisoning is methemoglobinemia. Methods The content of methemoglobin in blood samples of acute poisoning rats, rabbits, domestic pigeons and acute poisoning sodium nitrite were determined by cyanmethemoglobin hemoglobin colorimetry. Results The contents of methemoglobin in the blood samples of the acute poisoning chlordimeform animals were in the normal range, while the content of methemoglobin in the blood samples of acute poisoning sodium nitrite increased significantly. Sodium dimercaptopropanesulfonate could not be reduced by sodium nitrite Caused by methemoglobin. Conclusion Acute poisoning of chlordimeform is not the cause of all or most of methemoglobinemia. Methemoglobinemia is not the main cause of acute death of chlordimeform.