虽然一般公认强地松龙的药代动力学与剂量无关,而至今所做的研究示,强地松龙动力学可能与剂量有关。M.E.Pickup,J.R.Lowe,Patricia A.Le-atham,Valerie M.Rhind,V.Wri-ght 和 W.W.Downie 调查了六名46-68岁的骨关节住院病人和四名29-39岁的正常男人。三名病人同时接受抗风湿治疗,用Ibuprofen 或 Dextropropoxyphene 和Paracetamol,二名病人还用了 Nitragz-pam。没有人以前曾接受过激素治疗。强地松龙的剂量按每公斤体重0.15mg-0.3 Although it is generally accepted that the pharmacokinetics of prednisolone is independent of dose, studies done so far have shown that prednisolone kinetics may be dose related. M.E. Pickup, J.R.Lowe, Patricia A.Le-atham, Valerie M.Rhind, V.Wri-ght, and W.W. Downie investigated six 46-68 year-old patients with bone-joint disease and four normal men aged 29-39. Three patients also received antirheumatic treatment with Ibuprofen or Dextropropoxyphene and Paracetamol, and two patients also used Nitragz-pam. No one has previously received hormonal therapy. Prednisolone dose of 0.15mg-0.3 per kilogram of body weight