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研究了氟苯尼考(florfen icol)对杂色鲍Haliotis diversicolorReeve稚鲍96 h的急性毒性,其LC50为(162.67±17.41)mg/L(95%置信限)。稚鲍中毒后的临床症状为:分泌大量黏液,附着力明显减弱,内脏团膨大,对外界刺激反应迟钝,呈麻痹状。组织切片观察结果表明:鲍消化腺和肾脏损伤严重,其它器官未见明显病变;随着浸浴时间和药物浓度的增加,消化腺中消化细胞空泡化,并与嗜碱性细胞逐渐从基膜脱落解体,管间结缔组织胶原纤维断裂,呈弥散状广泛坏死;肾腔上皮细胞萎缩,与基膜分离,腔体变小,微绒毛脱落,中毒严重时,肾上皮细胞融合,核解体消失。
The acute toxicity of florfen icol to Haliotis diversicolor Reeve was studied at 96 h with LC50 of (162.67 ± 17.41) mg / L (95% confidence limit). After the clinical symptoms of juvenile abalone poisoning: secretion of a large number of mucus, adhesion was significantly weakened, visceral mass enlargement, unresponsive to external stimuli, was paralyzed. The histological sections showed that the digestive gland and kidney of abalone were severely damaged, and no obvious pathological changes were observed in other organs. With the increase of bath time and drug concentration, digestive cells in digestive gland were vacuolized, The membrane detachment and disintegration, collagen fibers in the connective tissue between the fracture, showing a wide range of diffuse necrosis; renal epithelial cells shrink, separated from the basement membrane, the cavity smaller, microvilli shedding, severe poisoning, renal epithelial cells fused, nuclear disintegration disappeared .