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细胞癌变与衰老主要受细胞染色体两端的重复序列—端粒 (ｔｅｌｏｍｅｒｅ ,ＴＬＭ )长度的控制。端粒起着分子钟或分子融丝的作用 ,是由端粒末端转移酶—端粒酶 (ｔｅｌｏｍｅｒａｓｅ ,ＴＬＭＡ)特异合成。近来有研究证明 ,端粒酶与细胞增生、分化和不死性有着极为密切的关系
Cell carcinogenesis and aging are mainly controlled by telomere (TLM) length, a repetitive sequence on both ends of the cell chromosome. Telomeres play the role of molecular clocks or molecular fusions and are specifically synthesized by telomerase (TLMA). Recent studies have shown that telomerase and cell proliferation, differentiation and mortality are closely related