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本文初步介绍了促胃液素的化学性质和一种新的提取方法。作者用与众不同的新方法从猪竇粘液中提得了等电点在pH15.0或pH8.0的促胃液素类似物。作者用pH11-12的碱液在40℃时提取,然后在pH5.0时进行多次等电点沉淀和在氯化钠溶液中多次沉淀,最后经透析和冰冻干燥,每20个猪竇粘液可得0.5—2.0gm的产品。本品具有良好的促胃液分泌作用,注射后[H~+]浓度和分泌速度迅速上升,半小时内活
This article initially introduced the chemical properties of gastrin and a new extraction method. The authors used a new and distinctive method to derive gastrin analogues with isoelectric point at pH 15.0 or pH 8.0 from porcine sinus mucus. The authors used pH 11-12 lye extraction at 40 ℃, and then at pH5.0 multiple isoelectric point precipitation and precipitation in sodium chloride solution, and finally dialysis and freeze-drying, every 20 pigs Mucus available 0.5-2.0gm of the product. This product has a good role in promoting gastric juice secretion, [H ~ +] concentration and secretion rate increased rapidly after injection, live within half an hour