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目的：研究ＳＰ１在乳腺腺病及乳腺癌组织中的分布。方法：采用ＡＢＣ免疫组织化学染色技术，对乳腺腺病及乳腺癌组织进行ＳＰ１的检测。结果：乳腺癌组织ＳＰ１阳性表达率为３６５９％；Ⅱ级腺病为６４５％；Ⅰ级腺病无阳性表达。结论：乳腺腺病及乳腺癌间ＳＰ１分布的显著性差异，表明ＳＰ１测定对于乳癌的判定具有一定意义
Objective: To study the distribution of SP1 in breast adenosis and breast cancer. Methods: ABC immunohistochemical staining technique was used to detect SP1 in breast adenosis and breast cancer. Results: The positive expression rate of SP1 in breast cancer tissue was 36.9%, grade II adenopathy was 6.4%, and there was no positive expression of grade I adenosis. Conclusion: The significant difference in SP1 distribution between mammary adenosis and breast cancer indicates that SP1 determination has certain significance for the determination of breast cancer.