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腹泻病在发展中国家发病率和死亡率均高,小儿患者尤多.近十年有关研究认为.以下3类大肠杆菌是急性细菌性腹泻的重要病原:①产肠毒素性大肠杆菌(简称 ETEC)。它能产生肠毒素,是发展中国家霍乱样腹泻的重要病原,也是“旅游者腹泻”的常见病原.②肠道侵袭性大肠杆菌(简称EIEC),与痢疾杆菌的病理学表现相似,能侵入肠道粘膜。④肠道致病性大肠杆菌(简称 EPEC),属于特殊的血清型,40年代末到60年代初曾在世界各地多次引起婴幼儿腹泻的暴发流行.本文以目前研究较多的 ETEC 为中心,对这3类大肠杆菌腹泻的研究现状作一简述.
Diarrheal disease in developing countries morbidity and mortality are high, especially in pediatric patients.Related studies in the past decade that the following three types of E. coli is an important pathogen of acute bacterial diarrhea: ① enterotoxigenic Escherichia coli (ETEC ). It can produce enterotoxin, which is an important pathogen of cholera-like diarrhea in developing countries and is also a common pathogen of “traveler’s diarrhea.” ② Intestinal invasive Escherichia coli (EIEC), similar to the pathological manifestation of Shigella dysenteriae, Intestinal mucosa. ④ Enteropathogenic pathogenic Escherichia coli (EPEC), which belongs to a special serotype, has caused outbreaks of infantile diarrhea in many parts of the world from the late 1940s to the early 1960s.This paper focuses on the current research on ETEC , A brief account of the current status of these three types of E. coli diarrhea.