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以正交设计筛选处方,研制了安心酮注射剂,考察了制剂的稳定性,有效期为2.85年。采用酸性染料比色法测定注射剂中安心酮的含量,平均回收率为98.7%(RSD=0.44%)。本品对离体灌流豚鼠心脏的作用与原药相似。
Orthogonal design to filter prescription, developed anxin ketone injection, investigated the stability of the preparation, valid for 2.85 years. The content of analgesic ketone in the injection was determined by acid dye colorimetry. The average recovery was 98.7% (RSD = 0.44%). This product on isolated perfused guinea pig heart and the role of the original drug similar.