尽管经过多年的工作,细胞毒性淋巴细胞和寄生原虫的杀伤机制仍未明确。一种著名的意见认为,由效应细胞表达的微孔形成蛋白,可在靶细胞浆产生液体通道,导致渗透性溶解和细胞死亡。对细胞毒性淋巴细胞的微孔形成活性(CTLs)自然杀伤细胞有影响的Perform是分子量为70kDa的蛋白,可从胞浆颗粒中分离出,随着排粒作用Perforin Despite years of work, the mechanisms of killing cytotoxic lymphocytes and parasitic protozoa remain unclear. One well-known opinion is that micropore-forming proteins expressed by effector cells can create liquid channels in the target cytoplasm resulting in osmotic lysis and cell death. Performing cytotoxic lymphocyte cytokinesis (CTLs) Natural killer cells Perform is a 70 kDa protein that can be isolated from cytoplasmic granules. With perforin