近 2 0余年 ,器官移植取得了很大进展 ,移植后急性排斥反应 (AR)发生率显著降低 ,移植物近期存活率明显提高 ,但是慢性排斥反应 (CR)的研究一直没有实质性突破 ,CR已成为远期移植物失功能的一个主要原因。CR多发生在器官移植数月后 ,包括临床和病理两方面含义 ,主要指在各种损 In the recent 20 years, great progress has been made in organ transplantation. The incidence of acute rejection (AR) after transplantation has been significantly reduced, and the recent survival rate of grafts has been significantly improved. However, there has been no substantial breakthrough in the study of chronic rejection (CR) Has become a major cause of long-term graft loss of function. CR occurred in a few months after organ transplantation, including clinical and pathological meaning of both, mainly refers to a variety of lesions