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对263例平原籍新战士在抵达青海省西宁市(海拔2260m)的当天和到达格尔木市(2800m)第10天、40天、80天分别进行了超氧化物岐化酶(SOD),谷胱甘肽过氧化物酶(GSH-Px)、过氧化氢酶(CAT)及丙二醛(MDA)测定。结果显示在进驻高原后40天SOD、CSH-Px、CAT测值和SOD/MDA的比值明显降低(P<0.01)并伴有MDA的显著升高(P<0.01),80天后上述指标进一步变化。表明平原人进驻高原后体内发生了一定程度的自由基代谢失衡,263例战士分为六组分别服用安慰剂、VitE、红景天、沙棘、枸杞等,结果服药组SOD、GSH-Px不仅未降低且有不同程度升高同时伴有MDA的下降。说明上述药物对高原低氧环境所致的自由基代谢失衡有调节、保护作用。
A total of 263 plain new soldiers arrived in Qinghai Province, Xining City (elevation 2260m) day and reached Golmud City (2800m) on the 10th, 40th and 80th days respectively superoxide dismutase (SOD), glutathione (GSH-Px), catalase (CAT) and malondialdehyde (MDA). The results showed that the ratio of SOD, CSH-Px, CAT and the ratio of SOD / MDA decreased significantly (P <0.01) and MDA significantly increased 40 days after entering the plateau (P <0.01) The above indicators further changes. Indicating that a certain degree of free radical metabolism imbalance occurred in the plain after entering the plateau. 263 soldiers were divided into six groups and received placebo, VitE, Rhodiola, seabuckthorn and medlar respectively. As a result, SOD and GSH-Px in the medication group were not only not Decreased and increased to some extent accompanied by the decline of MDA. These drugs on the plateau hypoxia caused by metabolic imbalance of free radical regulation and protection.