论文部分内容阅读
目的研究盐酸戊乙奎醚(长托宁)联合异丙酚在无痛肠镜检查中的应用。方法将2006年3月至2006年8月沈阳医学院沈洲医院麻醉科60例患者随机将患者分为2组。A组给予长托宁0.01mg/kg静脉注射,5min后给予异丙酚1～2mg/kg静脉注射,在30～40s内注完。B组单纯给予异丙酚1～2mg/kg静脉注射,在30～40s内注完。待患者进入睡眠状态后,睫毛反射消失,全身肌肉松弛,即可插入肠镜进行检查,检查中根据患者情况必要时追加异丙酚0.5mg/kg以维持麻醉深度。两组一般情况及用药前血压、心率、SpO2、呼吸频率无差异。结果用药后血压、心率、SpO2、呼吸频率在相同时点,差异无统计学意义(P>0.05),A组异丙酚用量、检查时间与B组差异有统计学意义(P<0.05)。结论长托宁联合异丙酚用于无痛肠镜的检查可以保证在检查过程中无任何痛苦,提供良好的操作环境,更安全、更可靠。
Objective To study the application of penehyclidine hydrochloride (long tonine) combined with propofol in painless colonoscopy. Methods From March 2006 to August 2006, 60 patients in Shenzhou Hospital of Shenyang Medical College were randomly divided into two groups. Group A was given ChangTopin 0.01mg / kg intravenous injection, propofol given after 5min 1 ~ 2mg / kg intravenous injection within 30 ~ 40s note. B group was given propofol 1 ~ 2mg / kg intravenously, and it was finished within 30 ~ 40s. When the patient goes to sleep state, eyelash reflex disappeared, muscle relaxation, you can enter the colonoscopy for examination, according to the patient’s condition if necessary, additional propofol 0.5mg / kg to maintain the depth of anesthesia. Two groups of general conditions and medication before blood pressure, heart rate, SpO2, respiratory rate no difference. Results There was no significant difference in blood pressure, heart rate, SpO2 and respiratory rate at the same time point after treatment (P> 0.05). The dosage of propofol in group A was significantly different from that in group B (P <0.05). Conclusions The combination of penehyclidine and propofol for painless colonoscopy ensures that there is no pain during the examination, providing a good working environment, safer and more reliable.