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本文对72名正常人及52例糖尿病(DM)患者进行了随意尿中总蛋白/尿肌酐(UProt/UCr)及白蛋白/尿肌酐(UAlb/UCr)比值测定,并与24小时尿总蛋白及白蛋白测定进行了比较,结果表明正常人UProt/UCr及UAlb/UCr水平(±SD)分别为33.0±28.8,9.5±3.5;DM患者UProt/UCr及UAlb/UCr水平升高,±SD分别为542.7±1293.7、447.3±1160.8(0.05>P>0.01,P<0.01);UProt/UCr与24小时尿总蛋白、UAlb/UCr与24小时尿Alb水平呈高度相关;UProt/UCr与24小时尿总蛋白、UAlb/UCr与24小时尿Alb阳性检出率无明显差异。结果提示随意尿UProt/UCr及UAlb/UCr完全可分别取代24小时尿总蛋白及白蛋白定量,作为DM患者尿蛋白监测的指标。
The urinary total protein / urinary creatinine (UProt / UCr) and albumin / urinary creatinine (UAlb / UCr) ratios in 72 normal subjects and 52 DM patients were measured and compared with 24 hours urine total protein The results showed that the levels of UProt / UCr and UAlb / UCr ( ± SD) were 33.0 ± 28.8 and 9.5 ± 3.5 in normal controls respectively. The levels of UProt / UCr and UAlb / UCr in DM patients were increased, ± UC were positively correlated with urinary protein levels of 24 hours urinary albumin and UProt / UCr, 24 hours urinary protein and UProt / UCr were significantly higher than that of 24 hours urinary albumin (P <0.01) Urine total protein, UAlb / UCr and 24-hour urine Alb positive detection rate no significant difference. The results suggest that urinary UProt / UCr and UAlb / UCr can completely replace 24-hour urinary total protein and albumin, respectively, as a marker of urinary protein in DM patients.