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目的研究肝海绵状血管瘤(CHL)的血供,探讨经肝动脉、门静脉治疗CHL。方法综合使用术中美兰染色,离体标本造影,剔除与肿瘤相邻的正常肝脏组织检查血管与肿瘤的关系,组织病理学连续切片等方法研究CHL供血血管的特点。结果美兰染色及造影显示肝动脉、门静脉参与供血,经肝静脉流出;与肿瘤相邻的血管大多数为小静脉样结构;连续切片未发现血管直接出入肿瘤,肿瘤边缘包膜中断处血管较多,动静脉结构共存,扩张血窦与肝组织混杂存在。2例不能手术切除的CHL施行肝动脉、门静脉分支结扎插管,并行硬化治疗取得近期疗效。结论CHL由肝动脉、门静脉双重供血,肝静脉为其流出道;对不能手术切除的CHL同时经肝动脉、门静脉介入治疗可取得较好的治疗效果。
Objective To study the blood supply of hepatic cavernous hemangiomas (CHL) and investigate the treatment of CHL via hepatic artery and portal vein. Methods Comprehensive use of intraoperative Meilan staining, in vitro angiography, removal of the normal liver tissue adjacent to the tumor to examine the relationship between blood vessels and tumors, and histopathological serial sections were used to study the characteristics of CHL blood supply blood vessels. Results The methylene blue staining and angiography showed that the hepatic artery and portal vein involved in blood supply and flowed out through the hepatic veins; the blood vessels adjacent to the tumor were mostly small vein-like structures; no blood vessels directly entered the tumor in consecutive sections, and the blood vessels at the edge of the tumor’s edge were interrupted. In many cases, arteriovenous structures coexist, and dilated sinuses and hepatic tissue are present together. Two cases of unresectable CHL performed hepatic artery and portal vein ligation and intubation. Parallel sclerotherapy achieved short-term efficacy. Conclusion CHL is supplied by the hepatic artery and portal vein, and the hepatic vein is its outflow tract. The interventional treatment of non-surgical CHL via hepatic artery and portal vein can achieve better therapeutic effect.