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目的:分析痰热清注射液致过敏性休克的临床特点,为临床安全用药提供参考。方法:检索《大医医学搜索》数据库,以“痰热清”、“休克”、“过敏反应”等为检索词,下载病例报告原文,然后对病例报告的有关资料进行统计与分析。结果:痰热清注射液致过敏性休克23例,均为静脉滴注给药;其中,速发型过敏性休克20例,迟发型3例,14例报告有联合用药情况,且大多是与高致敏药物联用;经积极的抗休克抢救,23例全部恢复正常。结论:正确选择用药人群,避免与高致敏药物联用,加强用药监测,积极应对用药中出现的任何不适反应是避免痰热清注射液致过敏性休克的重要措施。
Objective: To analyze the clinical features of Tanreqing Injection caused by anaphylactic shock and to provide reference for clinical safety medication. Methods: To search the database of “Great Medical Search” and search terms of “Tanreqing”, “Shock”, “Allergen” and so on, download the original case report, and then carry out the relevant data of the case report Statistics and Analysis. Results: Tanreqing injection caused anaphylactic shock in 23 cases, all of which were given intravenously. Among them, 20 cases were immediate haemorrhagic anaphylactic shock, 3 cases were delayed type. 14 cases reported combination therapy, and most of them were associated with hypersensitivity Drug combination; after active anti-shock rescue, all 23 cases returned to normal. Conclusion: The correct choice of drug users, to avoid combination with highly sensitized drugs, to strengthen drug monitoring, and actively respond to any discomfort in the medication is to avoid Tanreqing injection caused by an important measure of anaphylactic shock.