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目的探讨子宫全切除手术对患者卵巢内分泌功能、围绝经期症状及生存质量的影响。方法选取2013年3月至2015年3月来我院就诊治疗的98例子宫肌瘤患者作为实验研究对象,对所有患者实施子宫全切手术,观察分析患者手术治疗前后卵巢内分泌功能、围绝经期症状及生存质量状况。结果患者经过子宫全切手术治疗后,其雌二醇、促卵泡激素及黄体生成素水平与手术前相比差异显著,P<0.05;患者实施手术治疗后,有7例出现盗汗,13例脱发、便秘,阴道干涩及性交疼痛者分别是5例及4例,与治疗前相比(仅有3例出现脱发及便秘),临床并发症出现概率显著增加,P<0.05;患者术后性欲、性心理及性行为异常方面的BISF-W(国际女性性功能评估量表)值明显低于术前,P<0.05。结论子宫全切除手术能显著改善患者性激素状况,影响其卵巢功能,降低了性生活及生存质量。
Objective To investigate the effect of total hysterectomy on ovarian endocrine function, perimenopausal symptoms and quality of life. Methods A total of 98 patients with uterine leiomyoma treated in our hospital from March 2013 to March 2015 were enrolled in this study. Total hysterectomy was performed on all patients. Ovarian endocrine function, perimenopause, Symptoms and quality of life conditions. Results After total hysterectomy, the levels of estradiol, follicle stimulating hormone and luteinizing hormone were significantly different from those before operation (P <0.05). There were 7 cases of night sweats and 13 cases of hair loss after operation , Constipation, vaginal dryness and pain during intercourse were 5 cases and 4 cases, respectively. Compared with those before treatment (only 3 cases showed alopecia and constipation), the probability of clinical complications increased significantly (P <0.05). The postoperative libido, BISF-W (International Women’s Sexual Abilities Assessment Scale) was significantly lower than preoperative in terms of sexual psychology and sexual behavior (P <0.05). Conclusions Total hysterectomy can significantly improve the sex hormone status of patients, affect their ovarian function and reduce their sexual life and quality of life.