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目的分析男性尿路感染的病原谱,探讨防止男性尿路感染慢性化的途径。方法对男性尿道分泌物进行湿片及干片染色镜检和尿常规分析,明确有无尿道感染及病原体种类,检测滴虫和白念珠菌等;以细菌培养法检测淋球菌、加德纳菌、金黄色葡萄球菌、白念珠菌等致病菌,以免疫金标法检测衣原体等;按病原体的种类和种数进行数据统计。结果 1314例尿道分泌物共检出病原体12类2084株,根椐检出的病原体种类可将尿道炎细分为9种。多数急性尿道炎是由淋病奈瑟菌、支原体和衣原体等单一感染引起(580/736),菌株数为946株;由MCP、加德纳菌等多重感染引起的慢性尿道炎有431例,菌株数为1124株。两者病原体株数差异有统计学意义(P<0.01)。部分病例有5种以上病原体感染,部分病例镜检白细胞、红细胞、上皮细胞数明显异常,但培养均未检出细菌。结论急、慢性尿道炎的病原体有明显差异,尿道分泌物的病原谱分析可为临床正确诊断、治疗尿道炎症提供依椐。慢性尿道炎病例可出现MUBV现象及ASU病例。
Objective To analyze the pathogenic spectrum of male urinary tract infection and to explore ways to prevent the chronic urinary tract infection in men. Methods Male urethral secretions were subjected to microscopic examination of wet and dry pieces and routine urinalysis to determine whether there was any urinary tract infection and pathogen types, to detect trichomoniasis and Candida albicans, to detect gonococcal and gardnerella by bacterial culture , Staphylococcus aureus, Candida albicans and other pathogens to detect the chlamydia by immune gold standard; according to the types of pathogens and the number of data statistics. Results A total of 2084 strains of 12 kinds of pathogens were detected in 1314 cases of urinary tract exudates. The types of pathogens detected in root tissues could be divided into 9 kinds of urethritis. Most acute urethritis caused by a single infection (Neisseria gonorrhoeae, Mycoplasma and Chlamydia and other single infections (580/736), the number of strains of 946 strains; by MCP, Gardnerella and other multiple infections caused by chronic urethritis in 431 cases of strains The number of 1124 strains. There was a significant difference in the number of pathogens between the two strains (P <0.01). In some cases, more than 5 kinds of pathogens were infected. In some cases, the number of leucocytes, erythrocytes and epithelial cells was obviously abnormal, but no bacteria were detected in culture. Conclusion The pathogens of acute urethritis and chronic urethritis have obvious difference. The pathogenic spectrum analysis of urethral discharge can provide correct diagnosis and treatment of urethral inflammation. Chronic urethritis cases may occur MUBV phenomenon and ASU cases.