早在100余年前已有严重肝功能障碍出现肾功能不全的报道,那时已经发现多数患酒精性肝硬化和腹水的病人伴有肾功能衰竭,但是肾脏的组织学病变并不显著。约40年前肝肾综合征(HRS)方才得到明确的认识。肝功能障碍出现肾功能衰竭的特征是除肾脏排钠非常低外,且无蛋白尿。人们注意到其它病理生理改变,认识到肝肾综合征是。肾脏内血管收缩所引起 As early as 100 years ago there have been reports of severe renal dysfunction with renal insufficiency. At that time, most patients with alcoholic cirrhosis and ascites were found to have renal failure, but the renal histological lesion was not significant. About 40 years ago, liver and kidney syndrome (HRS) had just been a clear understanding. Renal dysfunction occurs in renal failure characterized by very low renal excretion of sodium, and no proteinuria. People have noticed other pathophysiological changes, recognizing that hepatorenal syndrome is. Kidney caused by vasoconstriction