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[目的 ]探讨珍珠梅乙酸乙酯提取物的抗肿瘤作用 .[方法 ]按照标准方法给 3 6只小鼠接种S180 肉瘤后 ,随机分成 3组 :实验 1组 :每天灌胃珍珠梅提取物 16.7g/kg ;实验 2组 :每天灌胃珍珠梅提取物 8.4 g/kg ;对照组 :每天灌胃生理盐水 10mL/kg ;各组均连续给予 10d ,观察瘤重及体重 .[结果 ]16 7,8 4 g/kg珍珠梅乙酸乙酯提取物对S180 肉瘤的抑制率分别为 4 6% ,5 7% ,实验组与对照组体重变化无显著性差异 .[结论 ]珍珠梅乙酸乙酯提取物对小鼠S180 肉瘤有抑制作用
[Objective] To investigate the antitumor effect of ethyl acetate extract of pearl plum. [Methods] Thirty six mice were inoculated with S180 sarcoma according to the standard method and then randomly divided into three groups: experimental group 1: pearl plum extract 16.7 g / kg; experimental group 2: oral administration of plum plum extract 8.4 g / kg daily; control group: normal saline 10 mL / kg every day; continuous administration for 10 days in each group to observe tumor weight and body weight. [Result] , Respectively. The inhibitory rates of ethyl acetate extract of pearl plum plum blossom on S180 sarcoma were 46% and 57%, respectively. There was no significant difference in body weight between the experimental and control groups. [Conclusion] S180 sarcoma mice have inhibitory effect