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目的为提高临床肝癌预防工作质量,进一步为准确诊断提供依据,特对癌胚抗原联合甲胎蛋白检测在肝癌鉴别诊断中的应用价值进行分析探讨。方法本文以87例肝癌患者作为研究对象,其中原发性肝癌(PHC)患者46例、转移性肝癌(MHC)患者41例并将50例健康体检人群作为对照组,运用电化学发光免疫分析法对他们血清中的甲胎蛋白(AFP)和癌胚抗原(CEA)含量进行检测。结果发现在PHC患者和MHC患者的血清中癌胚抗原双和甲胎蛋白的含量明显高于对照组中的含量,另外MHC患者中的癌胚抗原含量比PHC患者的明显高出许多。结论针对人体血清癌胚抗原及甲胎蛋白指标进行检测,其结果属确诊肝癌重要的临床参考标准,且对于临床肝癌的诊断及防治工作也具有重要的指导价值。
Objective To improve the quality of clinical liver cancer prevention and further provide a basis for accurate diagnosis, especially for the detection of carcinoembryonic antigen combined with alpha-fetoprotein in the differential diagnosis of liver cancer for analysis. Methods Totally 87 patients with hepatocellular carcinoma were enrolled in this study. Among them, 46 patients with primary liver cancer (PHC), 41 patients with metastatic liver cancer (MHC) and 50 healthy controls were used as control group. Electrochemiluminescence immunoassay Their serum levels of AFP and CEA were measured. The results showed that in patients with PHC and MHC serum levels of carcinoembryonic antigen double and alpha-fetoprotein was significantly higher than the control group, in addition MHC patients with carcinoembryonic antigen content was significantly higher than PHC patients. Conclusion The detection of human serum carcinoembryonic antigen and alpha-fetoprotein index is an important clinical reference standard for diagnosis of hepatocellular carcinoma, and also has important guiding value for the diagnosis and prevention and treatment of clinical hepatocellular carcinoma.