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目的研究高空低气压环境对角膜接触镜、佩戴者视力和角膜的影响。方法 8名(16眼)男性近视受试者,屈光度为-0.5～-4.25 D,先后佩戴1种含水量为55%和2种含水量为38%的角膜接触镜,进行3次低压舱模拟高空环境实验,每次上升速率25 m/s,升至2500 m和5300 m各停留20 min,7000m停留20 min,然后以10～40 m/s的速率下降,每下降1500 m停留5 min。在每次实验前及实验过程中的每一个高度上升(或下降)前和实验后进行视力、裂隙灯显微镜检查和主观感觉评价。结果佩戴每一种镜片在不同高度之间和在不同高度佩戴3种镜片之间视力变化差异无统计学意义(P>0.05)。角膜接触镜透明度和角膜透明度无明显变化,未发现有镜下气泡形成,主观感觉视物清晰度、戴镜舒适性无明显变化,无光晕、虹视现象。结论在轻中度高空低气压环境中,佩戴软性角膜接触镜是安全的和可以耐受的。
Objective To study the effects of high altitude and low pressure environment on the contact lens, wearer’s eyesight and cornea. Methods Eight eyes (16 eyes) of male myopic subjects with diopters of -0.5 ~ -4.25 D were examined by wearing a contact lens with 55% water content and then 38% During the experiment at high altitude, the rate of ascending 25 m / s, rising to 2500 m and 5300 m respectively stayed for 20 min and 7000 m for 20 min, then decreased at the rate of 10-40 m / s. Visual acuity, slit lamp microscopy, and subjective sensory evaluations were performed before and after each elevation (or drop) in the experiment before and during each experiment. Results There was no significant difference in visual acuity between wearing each lens at different heights and wearing three lenses at different heights (P> 0.05). No significant changes in the transparency of the contact lens and corneal transparency, no bubbles were found under the microscope, subjective perception of visual clarity, wearing comfort no significant change, no halo, rainbow phenomenon. Conclusions Soft contact lenses are safe and tolerable in mild-moderate high altitude and low pressure environments.