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脑卒中是我国头号致死原因。其中脑桥梗死占所有急性缺血性脑卒中的7%,占后循环供血区梗死的15%[1]。急性脑血管病一般在72 h内因梗死区神经功能破坏或由于全身性因素等易导致神经功能早期恶化[2]。症状进展性加重的发生率约20%~50%,且直接影响患者的预后[3]。临床上由于脑桥梗死供血血管的特点,普通磁共振成像在预测其进展加重方面意义不大。目前国内外有关脑桥梗死进展相关研究并不多见,本研究着重对脑桥梗死病因、发病机制、临床表现、影像学特点及预后的研究进展予以阐述,增加临床对进展性脑桥梗死的认识。
Stroke is the number one cause of death in China. The pontine infarction accounted for 7% of all acute ischemic stroke, accounting for 15% of infarcts in the posterior circulation of the blood supply [1]. Acute cerebrovascular disease generally results in early deterioration of neurological function due to neurological dysfunction in the infarct area within 72 hours or due to generalized factors [2]. Symptoms of progressive aggravate the incidence of about 20% to 50%, and directly affect the prognosis of patients [3]. Clinically due to the characteristics of pontine blood vessels, general magnetic resonance imaging in predicting the progress of aggravating little significance. At present, there are few researches about the progress of cerebral pontine infarction at home and abroad. This research focuses on the research progress of the etiology, pathogenesis, clinical manifestations, imaging features and prognosis of pontine infarction, and increases the clinical understanding of progressive pontine infarction.