Based on an empirical sediment transport equation that reflects the characteristics of “more input, more output” for sediment-laden flow in rivers, a general sediment transport expression was developed, which can take into account the effects of upstream sediment input, previous cumulative sediment deposition, critical runoff for sediment initiation, and the differences in sediment particle sizes between the mainstream and tributaries. Then, sediment load equations for non-flood and flood seasons for the sub-reaches from Bayangaole to Sanhuhekou and from Sanhuhekou to Toudaoguai, as well as the whole Inner Mongolia reach from Bayangaole to Toudaoguai, were formulated based on data collected between 1952 and 2010. The corresponding sediment deposition and the cumulative values at each river reach were calculated using the proposed sediment transport equations for the period 1952 to 2010 according to the principle of sediment conservation. Comparisons between the calculated and measured values using the proposed sediment load equations for the sub-reaches and the entire reach showed that the calculated sediment load and sediment deposition and the corresponding cumulative values in the flood and non-flood seasons were in good agreement with the measured values. These results indicated that the proposed methods can be applied to calculate the sediment load and the associated sediment deposition in the flood and non-flood seasons for long-term trend analysis of sediment deposition in the Inner Mongolia reach of the Yellow River. Based on an empirical sediment transport equation that reflects the characteristics of “more input, more output ” for sediment-laden flow in rivers, a general sediment transport expression was developed, which can take into account the effects of upstream sediment input, previous cumulative sediment deposition, critical runoff for sediment initiation, and the differences in sediment particle sizes between the mainstream and tributaries. Then, sediment load equations for non-flood and flood seasons for the sub-reaches from Bayangaole to Sanhuhekou and from Sanhuhekou to Toudaoguai, as well as the whole Inner Mongolia reach from Bayangaole to Toudaoguai, were formulated based on data collected between 1952 and 2010. The corresponding sediment deposition and the cumulative values ​​at each river reach were calculated using the proposed sediment transport equations for the period 1952 to 2010 according to the principle of sediment conservation. Comparisons between the calculated and measure d values ​​using the proposed sediment load equations for the sub-reaches and the entire reach showed that the calculated sediment load and sediment deposition and the corresponding cumulative values ​​in the flood and non-flood seasons were in good agreement with the measured values. These results indicated that the proposed methods can be applied to calculate the sediment load and the associated sediment deposition in the flood and non-flood seasons for long-term trend analysis of sediment deposition in the Inner Mongolia reach of the Yellow River.