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目的：对正常人、龋病和牙髓炎患者牙髓组织中一氧化氮（Ｎｉｔｒｉｃｏｘｉｄｅ，ＮＯ）含量进行检测，初步探讨ＮＯ在牙髓组织自身修复中的作用。方法：采用荧光分光光度法检测其中亚硝酸根（ＮＯ２－）含量，以间接确定ＮＯ含量。结果：正常牙髓组织中ＮＯ无性别差异（Ｐ＞０．０５），浅龋组与对照组ＮＯ无显著性差异（Ｐ＞０．０５），而深龋伴慢性牙髓炎组ＮＯ含量则显著高于对照组（Ｐ＜０．０５）。结论：牙髓组织中ＮＯ含量的变化与其炎症反应有一定的联系，ＮＯ可能在牙髓炎症和自身修复过程中起到一定的作用。
Objective: To investigate the content of nitric oxide (NO) in dental pulp of normal subjects, dental caries and pulpitis patients and to explore the role of nitric oxide (NO) in dental pulp tissue repair. Methods: The content of nitrite (NO2-) was detected by fluorescence spectrophotometry to indirectly determine the content of NO. Results: There was no significant difference in NO between normal dental pulp tissue and control group (P> 0.05), while there was no significant difference in NO between shallow dental caries group and control group (P> 0.05) Significantly higher than the control group (P <0.05). CONCLUSIONS: The change of NO content in pulp tissue is related to the inflammatory reaction. NO may play a role in pulp inflammation and self-repair process.