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目的探讨血清CYFRA21-1的检测在甲状腺乳头状癌在诊断转移中的意义。方法选择我院2005年1月～2008年1月本院收治的甲状腺乳头状癌伴转移患者117例,分别测定患者血清中甲状腺球蛋白、CYFRA21-1的含量,并将两种检测的阳性率进行比较。结果甲状腺乳头状癌患者血清CYFRA21-1的阳性率为83.76%(98/117)明显高于甲状腺球蛋白的阳性率61.53%(72/117),差异有统计学意义(P<0.01)。结论血清CYFRA21-1和甲状腺球蛋白均可用于诊断甲状腺乳头状癌的转移,但前者的阳性率要高于后者。
Objective To investigate the significance of serum CYFRA21-1 in the diagnosis and metastasis of papillary thyroid carcinoma. Methods A total of 117 patients with papillary thyroid carcinoma with thyroid carcinoma admitted to our hospital from January 2005 to January 2008 were enrolled in this study. The serum levels of thyroglobulin and CYFRA21-1 were determined respectively. The positive rates of the two tests Compare. Results The positive rate of serum CYFRA21-1 in patients with thyroid papillary carcinoma was 83.76% (98/117), which was significantly higher than that of thyroglobulin (61.53%, 72/117). The difference was statistically significant (P <0.01). Conclusion Both serum CYFRA21-1 and thyroglobulin can be used in the diagnosis of papillary thyroid carcinoma metastasis, but the positive rate of the former is higher than the latter.