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目的探究特布他林联合布地奈德雾化治疗成人哮喘急性发作的疗效及对肺功能的影响。方法 100例哮喘急性发作患者,随机分为对照组和观察组,各50例。对照组采用布地奈德进行治疗,观察组联合特布他林和布地奈德雾化治疗。对比两组患者的临床疗效、临床症状消失时间、肺功能改善情况及不良反应发生率。结果观察组治疗总好转率为96.00%,明显高于对照组的62.00%,差异有统计学意义(P<0.05)。观察组患者的临床症状消失时间及肺功能改善情况均明显优于对照组,差异均有统计学意义(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论特布他林联合布地奈德雾化治疗成人哮喘急性发作临床效果显著。
Objective To investigate the efficacy and safety of terbutaline combined with budesonide in the treatment of acute asthma attack in adults. Methods One hundred cases of acute asthma attack were randomly divided into control group and observation group, 50 cases each. The control group was treated with budesonide, the observation group combined with terbutaline and budesonide atomization. The clinical efficacy, the disappearance of clinical symptoms, the improvement of pulmonary function and the incidence of adverse reactions were compared between the two groups. Results The total improvement rate of observation group was 96.00%, which was significantly higher than that of control group (62.00%), the difference was statistically significant (P <0.05). The disappearance of clinical symptoms and the improvement of pulmonary function in observation group were significantly better than those in control group, with significant differences (P <0.05). The incidence of adverse reactions in the two groups, the difference was not statistically significant (P> 0.05). Conclusion Terbutaline and budesonide are effective in treating acute exacerbation of adult asthma.