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目的观察血清囊虫IgG抗体在脑囊尾蚴病临床诊断中的价值。方法对临床确诊的1 266例脑囊尾蚴病患者作血清囊虫IgG抗体检测,将检测结果进行分析。结果 1 266例脑囊尾蚴病患者阳性689例,阳性率54.42%。685例急性期患者中阳性436例,阳性率63.65%;476例慢性期患者中阳性173例,阳性率36.34%;两组间阳性率差异有非常显著性意义(x~2=84.0,P<0.01)。520例急性期单发病灶患者阳性295例,阳性率56.73%,165例多发病灶患者阳性141例,阳性率85.45%,急性期单发灶与多发灶囊虫抗体阳性率差异有统计学意义(x~2=44.69,P<0.01)。385例慢性期单发病灶患者阳性126例,阳性率32.73%,91例多发病灶患者阳性47例,阳性率51.65%,慢性期单发灶与多发灶囊虫抗体阳性率差异有非常性显著意义(x~2=11.46,P<0.01)。混和期(急性期和慢性期病灶同时存在者)98例,阳性73例,阳性率74.49%;弥漫性(满天星病灶)患者7例,均为阳性。结论急性期脑囊尾蚴病抗体阳性率高于慢性期。急性期多发病灶者脑囊尾蚴病抗体阳性率高于急性期单发病灶者,慢性期多发病灶者脑囊尾蚴病抗体阳性率明显高于单发病灶者。
Objective To observe the value of serum cysticercosis IgG antibody in the clinical diagnosis of cerebral cysticercosis. Methods Serum cysticercosis IgG antibody was detected in 1 266 patients with cerebral cysticercosis clinically diagnosed. The detection results were analyzed. Results A total of 1 266 cases of cerebral cysticercosis were positive in 689 cases, the positive rate was 54.42%. The positive rate was 63.65% in 685 cases of acute phase, and 173 cases were positive in 476 cases of chronic phase, the positive rate was 36.34%. The difference between the two groups was significant (x 2 = 84.0, P < 0.01). There were 295 positive cases in 520 cases of acute single lesion, the positive rate was 56.73%. The positive rate of positive rate was 85.45% in 165 cases of multifocal lesion. The positive rates of single antibody and multiple cysticercosis antibodies in acute stage were statistically different x ~ 2 = 44.69, P <0.01). There were 126 positive cases in 385 patients with single chronic lesion, the positive rate was 32.73%. The positive rate was 51.65% in 91 patients with multiple lesions. The positive rates of single antibody and multiple cysticercosis antibodies in chronic phase were significantly different (x ~ 2 = 11.46, P <0.01). In the mixed phase (both acute and chronic lesions coexist), 98 cases were positive and 73 cases were positive, with a positive rate of 74.49%. In diffuse (Gypsophila lesion) patients, 7 cases were positive. Conclusion The positive rate of antibody of cerebral cysticercosis in acute phase is higher than that of chronic phase. The positive rate of antibody of cerebral cysticercosis in patients with multiple acute focal stages was higher than that in acute single stage. The positive rate of antibody of cerebral cysticercosis in patients with chronic multiple stage was significantly higher than that of single lesion.