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目的综述BMSCs在肿瘤治疗中的研究进展。方法广泛查阅近年国内外相关文献,对BMSCs肿瘤趋向性、与肿瘤组织生长的相互关系以及作为肿瘤治疗运载细胞的研究进行回顾性总结与分析。结果BMSCs对肿瘤组织具有体内定向迁移能力,可抑制或促进肿瘤组织生长,可以作为肿瘤基因治疗的运载细胞;但BMSCs具有向肿瘤转化的可能。结论BMSCs可能成为肿瘤治疗的良好运载细胞,但尚需进一步研究,以加强其在肿瘤治疗中的安全性。
Objective To summarize the research progress of BMSCs in the treatment of cancer. Methods Extensive access to relevant literature at home and abroad in recent years, the BMSCs tumor tendency, and the relationship between tumor growth and tumor-carrying cells as a study carried out retrospective review and analysis. Results BMSCs had the ability of targeted migration in vivo, which could inhibit or promote the growth of tumor tissue and could be used as the carrier of tumor gene therapy. But BMSCs have the possibility of transforming into tumor. Conclusion BMSCs may be a good carrier for tumor therapy, but further study is needed to enhance its safety in cancer treatment.