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目的观察早期积极复苏、镇静等治疗措施在防治严重创伤患者早期应激性溃疡中的作用。方法随机将严重创伤患者166例分为研究组(83例)和对照组(83例),研究组给予早期目标指导积极复苏、镇静等综合治疗,对照组在综合治疗的基础上加用H2受体阻滞剂或质子泵抑制剂等药物。观察2组患者胃液潜血情况。结果 2组治疗48h胃液潜血发生率差异无统计学意义(P>0.05),并且2组中12h内早期复苏与12h后晚期复苏者比较,前者48h胃液潜血的发生率明显低于后者(P<0.05)。结论严重创伤患者并发的早期应激性溃疡,早期给予积极的复苏治疗,减轻创伤应激反应,可能是防治其发生的最基本、最有力的方法 ,在临床实际工作中应引起足够的重视。
Objective To observe the effect of early recovery, sedation and other therapeutic measures in the prevention and treatment of early-stage stress ulcer in patients with severe trauma. Methods A total of 166 patients with severe trauma were randomly divided into the study group (83 cases) and the control group (83 cases). The study group was given early targets to guide active recovery and sedation, while the control group was given H2 treatment on the basis of comprehensive treatment Blockers or proton pump inhibitors and other drugs. Gastric occlusion in 2 groups was observed. Results There was no significant difference in the rate of gastric occult blood between the two groups at 48h (P> 0.05), and the rate of gastric occult blood 48h after 48h was significantly lower in the two groups than in the latter 12h <0.05). Conclusion Early stress ulcer complicated by severe traumatic patients may be the most basic and effective method to prevent and treat the early stress ulcer. It is necessary to pay more attention to the clinical practice.