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从细菌性心内膜炎病人中分离到的草绿色链球菌仍占所有病人之45～50%,其中5～10%对青霉素相当耐药。作者报告1例患法乐氏四联症已作Waterston分流术的9岁小儿,由于口服青霉素预防牙病失败,引起耐青霉素的草绿色链球菌感染,发展为细菌性心内膜炎。该患儿于入院当天作了6次血培养,均培养出草绿色链球菌,开始静脉滴注水剂青霉素40万u/kg/日,每4小时1次及庆大霉素5mg/kg/日,每8小时1次。每次给药时间不少于20分钟。于治疗第3天退热,症状改善,血培养转阴,共用药4周,治愈出院。随访2个月,健康情况一直良好。
Streptococcus viridans isolated from patients with bacterial endocarditis still accounts for 45 to 50% of all patients, of which 5 to 10% are fairly resistant to penicillin. The authors report that a 9-year-old pediatric patient who had tetralogy of Fallot who had undergone Waterston shunting developed penicillin-resistant dental caries streptococcal infection due to failure of oral penicillin to prevent dental problems and developed bacterial endocarditis. The child made 6 blood cultures on the day of admission, both of which cultivated Streptococcus viridans, started intravenous infusion of penicillin 400,000 u / kg / day, once every 4 hours and gentamycin 5 mg / kg / Day, every 8 hours 1 time. Each time not less than 20 minutes. 3 days in the treatment of fever, symptoms, blood culture negative, a total of 4 weeks, cured and discharged. Follow-up 2 months, the health condition has been good.