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目的对成都地区常住人群进行2型糖尿病(DM)及糖调节受损(IGR)发病相关的流行病学调查,了解成都地区居民2型DM及IGR的发病率,并探讨影响其发病的饮食相关危险因素。方法以2008年成都市两社区常住居民为调查对象,检测调查人群空腹血糖(FBG)和餐后2h血糖(2hGlu),并根据检测结果将人群分为正常组、IGR组和DM组。采用问卷调查方式获得被调查人群每日进食的种类和质量,计算热卡摄入量、食物成分的比例、每日电解质、维生素和微量元素的摄入量,并分析与DM及IGR的相关性。结果 2008年成都地区DM和IGR现患率分别为18.59%和24.22%;DM组热卡,食物脂肪、蛋白比例,钠摄入量高于正常组,而纤维素、食物碳水化合物比例、铁、锌、硒、锰的摄入量和维生素C、E摄入量低于正常组,差异均有统计学意义(P均<0.05);IGR组热卡、钠摄入量高于正常组,而纤维素、锌、硒、锰的摄入量和维生素C、E摄入量低于正常组,差异均有统计学意义(P均<0.05)。食物脂肪比例是影响DM的独立危险因素(OR=1.609)。维生素E是DM及IGR的独立保护因素(OR=0.733,0.990)。结论成都地区2型DM及IGR的现患率高于四川乃至全国其他地区平均水平。本地区糖尿病防治工作应重点关注长期脂餐和维生素E摄入不足的高危人群。
Objective To investigate the prevalence of type 2 diabetes mellitus (DM) and impaired glucose regulation (IGR) in resident population in Chengdu and to find out the incidence of type 2 DM and IGR in Chengdu residents and to explore the diet-related factors influencing their incidence Risk factors. Methods The residents of two communities in Chengdu in 2008 were investigated. Fasting plasma glucose (FBG) and 2h glucose (2h Glu) were measured in the surveyed population. According to the results, the subjects were divided into normal group, IGR group and DM group. The type and quality of daily food intake of the surveyed population were obtained by means of questionnaire, and the intake of caloric intake, the proportion of food ingredients, daily electrolytes, vitamins and trace elements were calculated and the correlations with DM and IGR were analyzed . Results The prevalence rates of DM and IGR in Chengdu in 2008 were 18.59% and 24.22% respectively. In the DM group, the calories, food fat, protein and sodium intake were higher in the DM group than those in the normal group. The ratios of cellulose to carbohydrate, iron and zinc , Selenium, manganese intake and vitamin C, E intake were lower than the normal group, the difference was statistically significant (P all <0.05); IGR group heat card, sodium intake was higher than the normal group, and fiber The intakes of vegetarian, zinc, selenium and manganese and vitamin C and E intake were lower than those of normal group (all P <0.05). The proportion of food fat was an independent risk factor for DM (OR = 1.609). Vitamin E is an independent protective factor for DM and IGR (OR = 0.733,0.990). Conclusion The prevalence of Type 2 DM and IGR in Chengdu is higher than that of other regions in Sichuan and the whole country. Diabetes prevention and treatment in the region should focus on long-term diet and vitamin E intake of high-risk groups.