百日咳病程中经常出现呼吸暂停和发绀,尤多见于小婴儿。然而,对引起这种危险并发症的发病机制并不清楚。病人和方法作者用非侵入的技术对年龄3周到7月的6名百日咳患儿进行了呼吸动作,气流和动脉血氧饱和度的整夜磁带跟踪记录。同时用12名年龄相仿的健康婴儿进行了对照的观察。根据持续一周以上的特殊性阵咳,伴恶心、呕吐、发绀、惊厥而做出诊断。所有的患儿都有呼吸暂停和快速发生的严重发绀。发绀和呼吸暂停可以突然出现,可于睡眠或清醒时发生,但常常不紧跟着咳嗽后出现。相反,许多情况下,发绀后而产生咳嗽。 Apnea often appears during the course of apnea and cyanosis, especially seen in small infants. However, the pathogenesis of this dangerous complication is unclear. Patients and Methods Authors Non-invasive techniques were used to record respiratory activity, airflow, and arterial oxygen saturation throughout the night in 6 children with pertussis who were 3 weeks to 7 months of age. At the same time with 12 healthy infants of similar age were observed. According to more than a week of the particular array of cough, with nausea, vomiting, cyanosis, convulsions and make a diagnosis. All children have apnea and rapid onset of severe cyanosis. Cyanosis and apnea can suddenly appear, can occur when sleeping or awake, but often do not appear immediately after the cough. On the contrary, in many cases, cough occurs after cyanosis.