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作者通过12年来对32例子宫平滑肌肉瘤的临床病理研究及文献复习认为:子宫平滑肌肉瘤具有特殊的病理性质,其发生仍为推论。发病率占所有子宫肉瘤的50~70%。原发性平滑肌肉瘤在子宫内呈弥漫性生长,继发性者局限于子宫平滑肌瘤内。本文对32例子宫平滑肌肉瘤的病理进行了核分裂计数、细胞分化程度、血管分布范围、坏死和出血等的研究,按Spiro及Koss提出的三级分数法进行分级,Ⅰ级:肿瘤保持平滑肌瘤的一般结构,但细胞较丰富并有不典型,较平滑肌细胞大,核浆比例增加,核染色质较多,核分裂相1~21个/10高倍视野(HPF);Ⅱ级:仍然保持良性平滑肌瘤
The author through 12 years of 32 cases of uterine leiomyosarcoma clinical pathology and literature review that: uterine leiomyosarcoma has a special pathological nature, the occurrence is still inferred. Incidence of all uterine sarcomas 50 to 70%. Primary leiomyosarcoma showed diffuse growth in the womb, secondary confinement in uterine leiomyoma. In this paper, 32 cases of uterine leiomyosarcoma pathology of mitotic count, the degree of cell differentiation, vascular distribution, necrosis and hemorrhage, etc., according to Spiro and Koss proposed three-grade fractionation grade, grade I: the tumor remains leiomyoma The general structure of the cells, but the cells more abundant and atypical, larger than the smooth muscle cells, the proportion of nuclear plasma increases, more nuclear chromatin, mitotic phase 1 ~ 21/10 high power field (HPF); Ⅱ grade: still maintain a benign and smooth Fibroids