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目的:探讨妊娠合并糖尿病孕妇同时并发子痫前期危险因素及对母婴的不良影响。方法:选取2013年2月至2015年5月东莞市虎门中医院和东莞市第五人民医院收治的53例妊娠合并糖尿病同时并发子痫前期患者为观察组,选取同时本院收治的68例妊娠合并糖尿病患者为对照组,比较两组患者年龄、产次、发病孕周、体质量指数(BMI)及母婴并发症。结果:观察组患者年龄、产次、BMI均大于对照组,且发病孕周小于对照组,组间比较,差异具有统计学意义(P<0.05)。观察组并发症中产后出血发生率高于对照组,组间比较,差异具有统计学意义(P<0.05)。观察组围产儿并发症中早产儿、新生儿窒息及新生儿低血糖发生率均高于对照组,组间比较,差异具有统计学意义(P<0.05)。结论:孕妇年龄、产次、体质量影响妊娠合并糖尿病同时并发子痫前期发病,可加重患者血管病变,影响子宫、胎盘,可增加母婴不良妊娠结局的发生。
Objective: To investigate the risk factors of preeclampsia and its adverse effects on mother and baby in pregnant women with gestational diabetes mellitus. Methods: From February 2013 to May 2015, 53 cases of concurrent preeclampsia with pregnancy complicated by diabetes mellitus in Humen TCM Hospital of Dongguan City and the Fifth People’s Hospital of Dongguan City were selected as the observation group. At the same time, 68 pregnant women Patients with diabetes mellitus were included as control group. Age, parity, gestational weeks, body mass index (BMI) and maternal and infant complications were compared between the two groups. Results: The age, parity and BMI of the observation group were greater than those of the control group, and the gestational age was smaller than that of the control group. The differences between the two groups were statistically significant (P <0.05). The incidence of postpartum hemorrhage in the observation group was higher than that in the control group. There was significant difference between the two groups (P <0.05). The incidence of perinatal complications in preterm infants, neonatal asphyxia and neonatal hypoglycemia were higher in the observation group than in the control group. The differences between the two groups were statistically significant (P <0.05). Conclusion: Age, birth time and body mass of pregnant women affect the incidence of pre-eclampsia with simultaneous diabetes mellitus in pregnancy, which may aggravate the vascular disease, affect the uterus and placenta, and increase the incidence of adverse pregnancy outcomes.