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急性髓系白血病(AML)是失去正常定向分化功能的非成熟的白血病细胞在体内堆积而产生异常造血的一种克隆性疾病。AML的年发生率约为1.8/10万人,65岁以上老年人的发病率已增加到17.2/10万人。启动及维持AML疾病过程的具有干细胞特性的极少数细胞,被定义为急性髓系白血病干细胞(AM
Acute myeloid leukemia (AML) is a clonal disease in which non-mature leukemic cells that lose their normal differentiation function accumulate in the body and produce abnormal hematopoiesis. The annual incidence of AML is about 1.8 / 10 million people, the incidence of elderly over the age of 65 has increased to 17.2 / 10 million people. A handful of cells with stem cell properties that initiate and sustain the AML disease process are defined as acute myeloid leukemia stem cells (AM