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目的:研究原发性青光眼患者术后心理状态及其影响因素。方法:回顾性病例研究。选取郑州大学第一附属医院2015年6月至2018年5月的184例原发性青光眼患者为观察组,100例健康体检者为对照组。观察组根据术后HADS评分而区分为抑郁焦虑组55例和无症状组129例,进行相关性分析。比较观察组手术前后的综合医院焦虑抑郁量表(HADS)的评分。结果:观察组术前及术后HADS评分和检出率均高于对照组,观察组术前HADS评分和检出率均高于术后,差异均有统计学意义(n P<0.05);抑郁焦虑组的年龄、病程、失眠、内向性格、单眼盲和闭角型青光眼比例均高于无症状组,差异均有统计学意义(n P<0.05);多因素Logistic回归分析显示,年龄[n OR=1.238,95%n CI(1.116~2.368)]、病程[n OR=0.968,95%n CI(0.438~1.529)]、青光眼类型[n OR=1.275,95%n CI(0.738~1.662)]和失眠[n OR=1.485,95%n CI(0.945~1.973)]可独立预测原发性青光眼术后抑郁焦虑程度。n 结论:原发性青光眼患者术后心理状态较差,年龄、病程、失眠和青光眼类型与术后心理状态具有一定相关性。“,”Objective:To study the psychological status and the influencing factors of patients with primary glaucoma after operation.Methods:This was a retrospective case study. Total of 184 cases with primary glaucoma from Jun.2015 to May 2018 in the First Affiliated Hospital of Zhengzhou University were selected as the observation group, and 100 healthy people were selected as the control group.The observation group was divided into 55 cases in the depression and anxiety group and 129 cases in the asymptomatic group according to the postoperative HADS scores.The clinical data between the two groups were compared with Logistic correlation analysis.The preoperative and postoperative Hospital Anxiety and Depression Scale (HADS) scores of the observation group were compared.Results:The preoperative and postoperative HADS scores and detection rates in the observation group were significantly higher than those in the control group, and preoperative HADS scores and detection rates in the observation group were significantly higher than those after operation, the differences were statistically significant (n P<0.05). The age, course of disease, the rate of insomnia, introversion, monocular blindness and angle closure glaucoma in the depression and anxiety group were significantly higher than those in the asymptomatic group, the differences were statistically significant (alln P<0.05). Multivariate logistic regression analysis showed that age[n OR=1.238, 95%n CI(1.116~2.368)], duration[n OR=0.968, 95%n CI(0.438~1.529)], type of glaucoma[n OR=1.275, 95%n CI(0.738~1.662)] and insomnia[n OR=1.485, 95%n CI(0.945~1.973)]could independently predict the degree of depression and anxiety after primary glaucoma surgery.n Conclusion:The psychological status of patients with primary glaucoma is poor after operation.The age, course of disease, insomnia and types of glaucoma are related to postoperative psychological status.