α,β-二溴苯丙酰氯与小分子有机胺反应可形成一对α-溴代桂皮酰胺的顺、反几何异构体。但其顺、反异构体的含量受胺摩尔比的影响。另外,苯环上取代基及反应介质也有一定影响。利用这种方法合成和制备薄层层析,分离得到间氯-α-溴代桂皮酰另丁胺、对溴-α-溴代桂皮酰异丙胺等八对几何异构体。 α, β-Dibromobenzene propionyl chloride and small organic amine can be formed by a pair of α-bromo cinnamate cis and trans geometric isomers. But its cis, trans isomer content by amine molar ratio. In addition, benzene ring substituents and reaction medium also have a certain influence. Using this method, thin layer chromatography was prepared and prepared, and eight pairs of geometric isomers were obtained, such as m-chloro-α-bromocinnamylbutylamine and p-bromo-α-bromooctylisopropylamine.