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目的:探讨三维适形放疗结合腔内后装放疗在宫颈癌治疗中的疗效及放疗并发症。方法:选取2008年4月~2012年12月确诊的宫颈癌70例为研究对象。随机分两组。单纯三维适形放疗治疗组为A组,35例,使95%等剂量曲线包绕靶区,肿瘤剂量50Gy,缩野加量至60Gy;3DCRT结合腔内后装组为B组,35例,肿瘤剂量50Gy,腔内照射5~6次,A点总剂量30~35Gy。结果:B组远期疗效明显高于A组,差异有统计学意义(P<0.05)。不良反应发生率B组明显低于A组,差异有统计学意义(P<0.05)。结论:三维适形放疗结合腔内后装放疗治疗是治疗宫颈癌的有效方法,可提高远期疗效并降低不良反应
Objective: To investigate the efficacy of three-dimensional conformal radiotherapy combined with endovascular radiotherapy in the treatment of cervical cancer and radiotherapy complications. Methods: Seventy patients with cervical cancer diagnosed from April 2008 to December 2012 were selected as the study subjects. Randomly divided into two groups. The simple three-dimensional conformal radiotherapy group was 35 cases in group A, 95% of the isodose curves were wrapped around the target area, the dose of tumor was 50Gy, and the amount of shrinkage was increased to 60Gy. Tumor dose 50Gy, intracavitary irradiation 5 to 6 times, A total dose of 30 ~ 35Gy. Results: The long-term curative effect of group B was significantly higher than that of group A, the difference was statistically significant (P <0.05). The incidence of adverse reactions in group B was significantly lower than that in group A, the difference was statistically significant (P <0.05). Conclusion: Three-dimensional conformal radiotherapy with intracavitary posterior radiation therapy is an effective treatment for cervical cancer, which can improve long-term efficacy and reduce adverse reactions