目的　探讨脂肪肝的发生与年龄、性别等因素的关系。方法　对 9389人进行健康体检、B超及实验室检查。结果　杭州地区脂肪肝平均患病率为 9 5 8%。其中 44岁以下组男性脂肪肝患病率为 5 70 % ,女性为2 35 % ,两组比较P <0 0 1;45～ 6 4岁组男女脂肪肝患病率剧增 ,且在同一水平 ,两者比较P >0 0 5 ;≥ 6 5岁组女性患病率明显高于男性 ,男女组分别为 11 92 %、32 5 5 % ,两组比较P <0 0 1。结论　脂肪肝的发生与年龄、性别有关 ,其患病率随年龄增长而增高 ,女性脂肪肝的发生可能尚与内分泌功能紊乱有关。 Objective To investigate the relationship between the occurrence of fatty liver and age, gender and other factors. Methods 9389 people were examined by physical examination, B ultrasound and laboratory tests. Results The average prevalence of fatty liver in Hangzhou area was 95.8%. Among them, the prevalence of fatty liver in 44-year-old men was 5 70% and that in female was 35%, P <0.01; the prevalence of fatty liver among men and women in 45-64 years old increased sharply and were at the same level , Respectively. The prevalence of females≥6 5 years old was significantly higher than that of males (11 92%, 32 5 5% respectively), P <0.01 for both groups. Conclusions The occurrence of fatty liver is related to age and sex, and its prevalence increases with age. The occurrence of fatty liver in women may still be related to endocrine dysfunction.