目的通过对60岁以上2型糖尿病患者骨密度与颈动脉内中膜厚度及斑块关系的分析,探讨骨量减低与动脉硬化的关系。方法对123例老年2型糖尿病患者行双能X线骨密度仪测定腰椎、髋部的骨密度,并行颈动脉超声检测颈动脉内中膜厚度及斑块,根据骨密度分为骨量正常及骨量减低组,并对它们进行相关分析。结果老年2型糖尿病患者,骨量减低组动脉动脉硬化的发生率为60.8%,高于骨量正常组的41.7%,差异有统计学意义(P<0.05)。结论骨量改变与动脉硬化有密切的关系,是否可作为骨量变化敏感的预测因子有待扩大病例数作进一步观察。 OBJECTIVE: To analyze the relationship between bone mineral density (BMD) and carotid intima-media thickness and plaque in type 2 diabetic patients over 60 years old and to explore the relationship between osteopenia and arteriosclerosis. Methods Bone mineral density (BMD) of the lumbar spine and hip were measured by dual-energy X-ray absorptiometry in 123 elderly patients with type 2 diabetes mellitus. Carotid artery intima-media thickness and plaque were detected by carotid ultrasonography. According to BMD, bone mineral density Osteopenia group, and their correlation analysis. Results The incidence of arterial atherosclerosis in elderly patients with type 2 diabetes mellitus was 60.8%, which was higher than that in normal group (41.7%) (P <0.05). Conclusions There is a close relationship between the change of bone mass and atherosclerosis. Whether it can be used as a predictor of bone mass change remains to be further expanded.