目的：比较不同潮气量对体重超重患者肺氧合功能的影响，寻求一种保护肺氧合功能通气模式。资料与方法：80例患者随机分为4个组：对照组（男/女）、实验组（男/女）。对照组潮气量=体重（kg）×8ml/kg，实验组潮气量=理想体重×8ml/kg。所有患者均采用丙泊酚、瑞芬太尼以及顺阿曲库铵诱导。气管插管后，按各组预设置的潮气量调节机械通气潮气量。丙泊酚复合瑞芬太尼持续靶控输注以及顺阿曲库铵间断静脉注射。机械通气开始时（T1）、机械通气1小时（T2）、手术结束时（T3）以及复苏拔管前（T4）分别作血气分析和监测气道压力。结果：1、对照组潮气量与实验组潮气量之间比较（P<0.05），有统计学意义。2、男对照组T3氧合指数（O I）<300例数与实验组分别是10例，3例；女对照组T3氧合指数<300例数与实验组分别是8例、1例；对照组T3氧合指数<300例数与实验组比较（P <0.05），有统计学意义。3、T2及T3动脉血二氧化碳分压（PaCO2）与实验组比较（P<0.05），有统计学意义。结论：实验组通气模式避免过度通气，减少肺氧合功能障碍风险，是一种“小潮气量”肺保护通气模式。“,”Objective: To compare the different tide volumes’impact on pulmonary oxygenation function in over weight patients, a kind of ventilation model which could protect pulmonary oxygenation function was found .Material and Method : 80 patients were be randomly divided into 4 groups: the male control group, the female control group, the male experiment group and the female control group. The control group’s tidal volume (VT) = body weight × 8ml/kg, the experiment group’s VT = ideal body weight×8 ml/kg. Propofol, remifentanil and cis-atracurium were respectively adopted to al patients by vein, during induction of anesthesia. After tracheal intubation, the ventilation of tidal volume were adjusted to each group’s preset volume tide. Propofol and remifentanil also were continuously target control infused during maintenance of anesthesia . Cis-atracurium was discontinuously used by vein . The blood gas analysis and air way pressure were respectively monitored at mechanical ventilation start(T1), the post mechanical ventilation 1 hour(T2) , the end-operation (T3) and the respiratory recovery before extubation (T4).Results: 1.The volume tide in the control group and in the experiment group were compared(P <0.05). The difference was significant.2. Patients which oxygenation index(OI) at T3 less than 300 in the female control group and these in the female experiment group were 8, 1 , respectively. Patients whose oxygenation index at T3 were less than 300 in the male control group and those in the male experiment group were 10, 3, respectively. Patients whose oxygenation index at T3 was less than 300 in the male control group and those in the experiment group was compared(P <0.05), the difference was significant . 3.The arterial carbon dioxide pressure(PaCO2) at T2 and PaCO2 at T3 in the control group and in the experiment group were compared respectively(P <0.05), the difference was significant Conclusion: The ventilation model in the experiment group avoided hyperventilation and decrease the risk of Pulmonary oxygenation dysfunction than in the control group. It was a kind of little tide volume pulmonary protected ventilation model.