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目的 探讨血钠、血浆皮质醇（ＣＯＲ）、醛固酮（ＡＬＤ）水平变化在脑卒中发病及演变中的意义。方法 测定单纯脑卒中组、并发高渗性昏迷组及正常人的血钠、ＣＯＲ、ＡＬＤ水平的变化。结果 并发高渗性昏迷（ＨＤＣ）死亡组与存活组、单纯脑卒中组三者间及与正常对照组间血钠、ＣＯＲ、ＡＬＤ水平比较均有显著性差异（Ｐ＜ ０．０５～０．００１）；随着病情的好转，ＣＯＲ、ＡＬＤ也逐渐恢复至正常水平。结论 血钠、ＣＯＲ、ＡＬＤ水平的变化与病情演变紧密相关，可作为判断病情轻重与预后的一项重要指标。
Objective To investigate the significance of serum sodium, plasma cortisol (COR) and aldosterone (ALD) levels in the pathogenesis and evolution of stroke. Methods The levels of serum Na, COR and ALD in the patients with stroke group, hyperosmolar coma group and normal subjects were measured. Results There were significant differences in serum sodium, COR and ALD levels between death group and survivors group, stroke group and normal control group (P <0.05-0). 001). With the improvement of the disease, COR and ALD gradually returned to their normal levels. Conclusion The changes of blood sodium, COR and ALD are closely related to the evolution of the disease, which can be used as an important index to judge the severity and prognosis of the disease.