对５４例卵巢癌和６８例良性疾病患者进行腹水或腹腔液β２－ＭＧ、ＣＥＡ、ＳＡ含量测定。发现卵巢癌患者腹水中的β２－ＭＧ、ＣＥＡ、ＳＡ平均含量均高于良性疾病患者。用阶梯分割线法分析了ＳＡ＋β２－ＭＧ和ＳＡ＋ＣＥＡ联合应用的结果，提示双标志物联合测定的诊断特异性、敏感性和准确性均优于单一标志物。对卵巢良、恶性腹水的鉴别诊断有一定的参考价值。 54 cases of ovarian cancer and 68 cases of benign disease in patients with ascites or peritoneal fluid β2-MG, CEA, SA content determination. Found that ascites in patients with ovarian cancer β2-MG, CEA, SA average levels were higher than in patients with benign diseases. The results of the combined application of SA + β2-MG and SA + CEA were analyzed by the ladder-dividing line method, suggesting that the diagnostic specificity, sensitivity and accuracy of the combined determination of both markers were better than single markers. On the differential diagnosis of benign and malignant ovarian ascites have a certain reference value.