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胃肠道出血部位的定位常很困难,而且病人的情况又不适宜用侵入性方法(如内腔镜及血管造影术)探查。Alavi等曾应用可很快地从血中清除的~(99m)锝硫胶体,在狗实验中可以测定慢至0.05～0.1ml/分的出血。作者参照Alavi的方法,用~(99m)锝标记热处理红细胞(HT/RBC)测定胃肠道出血。材料与方法:10只雌狗用硫喷妥钠麻醉,导管置入殷动脉,一端连接至输液泵,另一端插入小肠袢的腔内。在用血灌注此系统后,静脉注入已在49℃中加热10分钟的自体~(99m)锝红细胞。(注意加热时间不应超过15分钟,温度范围应为49°±5℃。若高于此温
Location of gastrointestinal bleeding is often difficult to locate, and the patient’s condition is not appropriate to use intrusive methods such as endoscopic and angiographic exploration. Alavi et al. Have used ~ (99m) technetium sulfur colloids that are rapidly cleared from the blood and can measure bleeding as slowly as 0.05 to 0.1 ml / min in dog experiments. The authors refer to Alavi’s method, with ~ (99m) technetium labeled heat-treated red blood cells (HT / RBC) for the determination of gastrointestinal bleeding. MATERIALS AND METHODS: Ten female dogs were anesthetized with thiopental. The catheter was placed in an inflamed artery, one end connected to an infusion pump and the other end inserted into the lumen of the small intestine. After this system was infused with blood, autologous ~ (99m) Tc red blood cells that had been heated at 49 ° C for 10 minutes were intravenously infused. (Note that the heating time should not exceed 15 minutes, the temperature range should be 49 ° ± 5 ℃. If above this temperature