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3、用药对鱼类病原菌耐药性的影响 鱼类病原菌耐药菌株的增加与滥用药物是分不开的。这主要是因为与养殖水体和养殖鱼类相比,从天然水体和野生鱼类分离的耐药菌株较少;耐药菌株的分布存在地域差异,用药少的鱼场耐药菌株出现率一般比用药多的鱼场低;病原菌对某一种(类)抗菌药物耐药性的产生与消失与生产中该种药物的使用或废止息息相关,如果在一段时间内反复大量使用同一种抗菌药物往往导致相应的
3, the impact of drug resistance of fish pathogens Fish resistant strains of pathogens increased with drug abuse are inseparable. This is mainly because there are fewer drug-resistant strains isolated from natural water and wild fish compared to farmed fish and farmed fish; there are geographical differences in the distribution of drug-resistant strains. The incidence of drug-resistant strains in fish farms with less medication is generally lower The use of more drugs in fish farms; pathogenic bacteria for a certain kind of (antimicrobial) drug resistance and the disappearance of the production and use of the drug or abolished, if over a period of time repeatedly using the same antimicrobial drugs often lead to corresponding