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目的评估尿促黄体生成素ＬＨ酶联免疫法预测排卵的临床价值。方法对３３例月经周期正常的育龄妇女，应用尿（ＬＨ）酶联免疫法进行排卵监测，结合阴道超声、血清ＬＨ和孕酮水平、宫预粘液评分等综合评价。结果３３个月经周期均有排卵，发生在周期１４．３８±１．６０天，平均最大卵泡直径１８．９６±２．１７ｍｍ（１６．３～２４．０ｍｍ）；尿ＬＨ显色阳性距排卵时间为２３．６±４．３ｈ，尿ＬＨ阳性２４ｈ和４８ｈ内发生排卵的阳性预测值分别为７８．８％和９７％。结论尿ＬＨ酶联免疫法是一种既准确又经济预测排卵的有效方法，可在阳性４８ｈ内实施不孕症的治疗。
Objective To evaluate the clinical value of urinary luteinizing hormone (LH) enzyme-linked immunosorbent assay in predicting ovulation. Methods A total of 33 women of childbearing age with normal menstrual cycle were enrolled in this study. Ovulation was monitored by enzyme-linked immunosorbent assay (ELISA). Combined with vaginal ultrasound, serum LH and progesterone levels, Results All 33 menstrual cycles had ovulation, which occurred at 14.38 ± 1.60 days and the average diameter of the largest follicles was 18.96 ± 2.17mm (16.3 ~ 24.0mm) 23.6 ± 4.3h. The positive predictive value of ovulation in urine LH positive 24h and 48h were 78.8% and 97% respectively. Conclusion Urinary LH enzyme-linked immunosorbent assay (ELISA) is an effective method to predict ovulation accurately and economically. It can be used to treat infertility within 48 hours after it is positive.